China MoARA Derecognizes the Usage of Metalaxyl-M Mixtures targeting Fusarium and Rhizoctonia solani Rice Diseases

China eliminates the rice seed/seedling uses of single-purpose Metalaxyl-M mixtures targeting Fusarium and Rhizoctonia solani related diseases. This is the first time China issued an injunction/restriction on specific usage due to efficacy consideration, and this move is interpreted by the industry as an important step in the national strategy of pesticide use reduction and rationalization.

China MoARA Derecognizes the Usage of Metalaxyl-M Mixtures targeting Fusarium and Rhizoctonia solani Rice Diseases On April 27th, 2020, the Chinese Ministry of Agricultural and Rural Affairs (MoARA) issued Announcement 275 to eliminate the registration of Metalaxyl-M seed/seedling-use mixtures targeting only blight and bakanae diseases caused by Fusarium and Rhizoctonia solani. A total of 24 affected registered formulations from 21 companies, including Syngenta and Sipcam are required to supplement field trial data.

As of the date of the promulgation, MOARA has stopped accepting or approving any rice-use application of Matalaxyl-M seed and seedling treatment mixtures targeting only Fusarium and Rhizoctonia solani related diseases. Existing registrants may apply for label expansion on other rice diseases caused by Pythium or Achlya by submitting a 1-year efficacy trial report in at least four sites as well as other supplemental data as per the “Announcement 2569-Data Requirements on Pesticide Registration”. The deadline for the data submission will be June 30th, 2021. Otherwise, the registration will be canceled accordingly.

Since regulatory reform in 2017, China elevated the requirements on multi-element formulations. Usage of combinations of different active ingredients needs to prove synergistic or resistance-delay effect above any corresponding single-element formulation. This must be supported by scientifically-designed laboratory test or field trial data generated in China. That is, any of the active ingredients used in the multi-element formulation should be proved effective against each pathogen claimed. The MoARA agronomists from the Expert Committee of Chinese National Pesticide Committee, the proposer of this Measure, clarifies that metalaxyl and Metalaxyl-M have effects on fungi such as Pythium, Pchlya, phytophthora, and Peronospora pathogens, but their effect against Fusarium and Rhizoctonia solani related rice diseases through seed, or seedling application is negligible. Hence such single-purpose usage shall no longer be acceptable. This the first time China issued an injunction/restriction on specific usage due to efficacy consideration, and this move is interpreted by the industry as an important progress in the national strategy of pesticide use reduction and rationalization.

Multi-element Rice Seed/Seedling Treatments Containing Metalaxyl-M Subject to Label Expansion by June 30th 2021

No.

ICAMA Registration Number

Composition

Formulation Type

Validity

Rice Pest/Disease registered

Registrant

1

PD20190243

Thiamethoxam 7.5%
Fludioxonil 1%

Flowable concentration (stable suspension)

2024/12/25

Bakanae disease
thrips

Liaoning Zhuangmiao Biotech Co.,LTD.

辽宁壮苗生化科技股份有限公司

2

PD20190236

Azoxystrobin 2.5%
Fludioxonil 1%
Metalaxyl-M 1.5%

Flowable concentration(stable suspension)

2024/12/25

bakanae disease

Liaoning Zhuangmiao Biotech Co.,LTD.
辽宁壮苗生化科技股份有限公司

3

PD20190114

Thiamethoxam 22.2%
Metalaxyl-M 1.7%
Fludioxonil 1.1%

Flowable concentration (stable suspension)

2024/8/19

Bakanae disease
thrips

Hunan Dafang Agricultural Chemical Co.,LTD.

湖南大方农化股份有限公司

4

PD20183997

Metalaxyl-M 5%
Hymexazol 25%

Soluble concentration

2023/8/20

blight

Jiangsu Greenscie Chemical Co.,LTD.

江苏耘农化工有限公司

5

PD20182728

Metalaxyl-M 37.5g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2023/7/23

Bakanae disease

Shanghai Hulian Biopharmaceutical Co.,LTD.

上海沪联生物药业(夏邑)股份有限公司

6

PD20182674

Tebuconazole 4%
Metalaxyl-M 2%
Azoxystrobi 4%

Coating suspension(film-forming)

2023/7/23

Bakanae disease

SIPCAM USA

美国世科姆公司

7

PD20182163

Metalaxyl-M 4%
Hymexazol 28%

Seed treatment solution

2023/6/27

blight

Shaanxi TupSen Biotech Co.,LTD

陕西汤普森生物科技有限公司

8

PD20180678

Metalaxyl-M 4%
Hymexazol 28%

Seed treatment solution

2023/2/8

blight

Jiangsu Mindleader Crop Science Co.,LTD

江苏明德立达作物科技有限公司

9

PD20180484

Thiamethoxam 15%
Metalaxyl-M 3%
Fludioxonil 2%

Coating suspension(film-forming)

2023/2/8

Bakanae disease
thrips

Haite Agrochemcial Co.,LTD of Hunan Agricultural University

湖南农大海特农化有限公司

 

PD20172755

Fludioxonil 25g/L
Metalaxyl-M          37.5g/L

Coating suspension(film-forming)

2022/11/20

Bakanae disease

Nanjing Goodagro Co.,LTD

南京高正农用化工有限公司

11

PD20172045

Thiamethoxam 22.2%
Metalaxyl-M 1.7%
Fludioxonil 1.1%

Coating suspension(film-forming)

2022/9/18

Bakanae disease
thrips

Shandong Qingdao Aodisi Biotech Co.,LTD.

山东省青岛奥迪斯生物科技有限公司

12

PD20171882

Thiamethoxam 22.2%
Fludioxonil 1.1%
Metalaxyl-M 1.7%

Coating suspension(film-forming)

2022/9/18

Bakanae disease
thrips

Hunan Suncas Agricultural Development Co.,LTD.

湖南新长山农业发展股份有限公司

13

PD20171349

Thiamethoxam 22.2%
Fludioxonil 1.1%
Metalaxyl-M 1.7%

Coating suspension(film-forming)

2022/7/19

Bakanae disease

Shandong Qingdao Aodisi Biotech Co.,LTD.

山东省青岛奥迪斯生物科技有限公司

14

PD20171173

Metalaxyl-M 10g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2022/7/19

Bakanae disease

Jiangsu Essence Fine-chemical Co.,LTD.

江苏艾津农化有限责任公司

15

PD20171139

Metalaxyl-M 10g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2022/7/19

Bakanae disease

Zhejiang Tianfeng Biological Science Co.LTD

浙江天丰生物科学有限公司

16

PD20170556

Metalaxyl-M 2%
Thiamethoxam 22%
Fludioxonil 1%

Coating suspension(film-forming)

2022/4/10

Bakanae disease
thrips

Nantong Chemical Technological Development Co.,LTD of Shenyang Research Institute of Chemical Industry

沈阳化工研究院(南通)化工科技发展有限公司

17

PD20170309

Metalaxyl-M 1.8%
Fludioxonil 0.6%
Azoxystrobin 3.6%

Coating suspension(film-forming)

2022/2/13

Bakanae disease
blight

Harbin Huolongshen Agricultural and Biotech Co.,LTD.

哈尔滨火龙神农业生物化工有限公司

18

PD20170058

Metalaxyl-M 37.5g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2022/1/7

Bakanae disease

Hangzhou Udragon Chemical Co., LTD.

浙江省杭州宇龙化工有限公司

19

PD20160154

Metalaxyl-M 3.3%
Fludioxonil 1.1%
Azoxystrobin 6.6%

Coating suspension(film-forming)

2021/2/24

Bakanae disease

Jiangxi Weilite Biotech Co.,LTD.

江西威力特生物科技有限公司

20

PD20150641

Metalaxyl-M 37.5g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2025/4/16

Bakanae disease

Syngenta(Nantong)

先正达南通作物保护有限公司

21

PD20142054

Tebuconazole 0.25%
Metalaxyl-M 0.55%

Seed treatment emulsion

2024/8/27

Blight

Heilongjiang Mudanjiang Rice Seedling Strengthening Agent Factory

黑龙江省牡丹江市水稻壮秧剂厂

22

PD20132145

Metalaxyl-M 5%
Hymexazol 25%

Soluble Liquid

2023/10/29

Blight

Jilin Changchun Changshang Pesticide Co.,LTD.

吉林省长春市长双农药有限公司

23

PD20131939

Metalaxyl-M 0.5%
Hymexazol 2.5%

Soluble Liquid

2023/10/9

Blight

Jilin Changchun Changshang Pesticide Co.,LTD.

 

吉林省长春市长双农药有限公司

24

PD20096644

Metalaxyl-M 37.5g/L
Fludioxonil 25g/L

Coating suspension(film-forming)

2024/9/2

Bakanae disease

Syngenta(Switzerland)

瑞士先正达作物保护有限公司

Reference Link

MoARA Announcement 275(in Chinese)

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