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EU BPR: Active Substance Renewal Deadlines for 2025 and Beyond

As part of the EU Biocidal Products Regulation (EU BPR), active substance approvals must be renewed before their expiry date to continue being used in biocidal products. The European Chemicals Agency (ECHA) mandates that renewal applications be submitted at least 550 days before the expiry date. To avoid disruptions and ensure continued market access in Northern Ireland (NI), it is crucial to meet these upcoming deadlines.

Key Deadlines for Active Substance Renewals in EU


29 March 2025

  • Clothianidin (CAS 210880-92-5) – Product Type 18

  • 2-Methyl-2H-isothiazol-3-one (MIT) (CAS 2682-20-4) – Product Type 13

  • Glutaral (CAS 111-30-8) – Product Types 2, 3, 4, 6, 11, 12

  • Folpet (CAS 133-07-3) – Product Types 7, 9

29 June 2025

  • Copper, Granulated (CAS 7440-50-8) – Product Type 8

27 December 2025

  • Biphenyl-2-ol (CAS 90-43-7) – Product Types 1, 2, 4, 6, 13

  • Epsilon-Momfluorothrin (CAS 1065124-65-3) – Product Type 18

  • L-(+)-Lactic Acid (CAS 79-33-4) – Product Type 1

  • CMIT/MIT Mixture (CAS 55965-84-9) – Product Types 2, 4, 6, 11, 12, 13

  • PHMB (CAS 27083-27-8) – Product Type 4

29 June 2026

  • DBDCB (CAS 35691-65-7) – Product Type 6

  • OIT (CAS 26530-20-1) – Product Type 8

  • Ampholyt 20 (CAS 139734-65-9) – Product Types 2, 3, 4

  • Bacillus Amyloliquefaciens (CAS N/A) – Product Type 3

  • Cyromazine (CAS 66215-27-8) – Product Type 18

Consequences of Missing the Renewal Deadlines


Failure to submit a timely renewal application for the active substances listed above will result in the expiration of approvals. This means the substances cannot be used in biocidal products within the relevant product types in NI. Additionally, any products treated with these substances will be prohibited from being placed on the market in Northern Ireland.

Source: HSE

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