The Australian Pesticides and Veterinary Medicines Authority (APVMA) is soliciting public opinions until July 2 on the registration of new rodenticidal active ingredient Bromethalin and 8 associated formulations.

Bromethalin is a neuro-toxic rodenticide that damages the central nervous system by uncoupling oxidative phosphorylation during ATP synthesis. This, in turn, results in vacuolization of myelin and increased intracranial pressure through the build-up of cerebral spinal fluid, which permanently damages neural axons, thereby causing paralysis, convulsions, and death.

Currently, this active ingredient is registered in the USA, predominantly used to control anticoagulant-resistant Norway rats, roof rats, house mice and meadow voles

Bell laboratories, Inc. has applied to the APVMA for registration of Bromethalin active ingredients and formulations, intended for use in the control of anticoagulant-resistant rats and mice in and around industrial, commercial, agricultural, and domestic buildings.