The GLP principle was initially proposed by the US FDA, to ensure the accuracy, reliability and the traceability of test data. The US EPA subsequently implemented the GLP rules within its registration management of pesticide and chemicals. In 1978, the Organization for Economic Co-operation and Development (OECD) issued the “Principles of Good Laboratory Practice” and pushed forward implementation within its member states. Meanwhile, OECD also accepted other non-OECD countries to join its MAD (Mutual Acceptance of Data) system. Currently South Africa, Israel and India have joined OECD’s MAD. However GLP development in China is far behind that of its OECD counterparts despite its dominating position in agrochemical production and exportation. China has not yet joined the MAD system and only a small percentage of its domestic labs are recognized as GLP-compliant by the monitoring authority from OECD members. Much of the safety assessment data obtained by Chinese laboratories is not accepted for pesticide registration by OECD member countries. Chinese companies that wish to export to OECD states must conduct their testing in OECD GLP accredited laboratories which can often mean duplication of testing and heavy financial input. The Chinese authority therefore established its own GLP management system and seek data acceptance by intergovernmental cooperation with other countries.