Four major aspects associated with efficacy data requirements have been clearly defined in the new regulation: comparative analysis with existing pesticide, resistance management, efficacy validation test by subsequent applicant and necessary data to justify the scientificness of multiple compound pesticides.

On 28 Jun 2016, China ICAMA issued the “Interim Guideline on the Field efficacy Trial Sites of Pesticide Registration”, which includes the requirements for trial location of 20 major crops and over 140 pests and diseases and will take effect on 1 Aug 2016.

On 14 Jun 2016, Brazil ANVISA approved a regulatory initiative to amend the procedure for pesticide reevaluation, aim at bringing more transparent and predictability during reevaluation process of pesticide with evidence of altered risk to human health.

According to a survey result revealed by a local newspaper, La Nación, total sales of Argentine agrochemical companies were 2.4 billion USD in 2015, a significant decrease of 16.7% on the previous year of 2.9 billion USD. The five largest companies: Monsanto, Syngenta, Dow AgroSciences, Bayer and Athanor suffered revenue decline of 455.1 million USD, representing 92.2% of the market decline.

On 6 Jun 2016, China ICAMA issued an interim guideline,  “Guideline on Crop/Area Distribution for the Residue Study of Pesticide Registration”, which will take effect on 1 Aug 2016.

Recently, Ministry of Agriculture of Malaysia released guideline for biopesticide registration. In the guideline, the MOA mainly provide data requirements for microbial and botanical registration.

On 11 May 2016, Brazil National Health Surveillance Agency (ANVISA) published a technical note to specify two exemption conditions for acute inhalation toxicity test for pesticide formulation and the applicable result for toxicological classification of pesticide. In Brazil, the inhalation toxicity data are mandatorily required for pesticide registration and the study should be performed under internationally recognized methods and the OECD test protocols most often accepted. The latest OECD Test Guideline 403-Acute Inhalation Toxicity has been appended with new procedures and parameters for lethal concentration inhalation study. ANVISA deems it is necessary to consolidate the technical reference with the requirement, acceptability and interpretation of study result to determine the endpoint.