Recently, the 19th Pesticide Information Exchange Conference was held in Nanjing. Vice director of ICAMA Mr. Zhao Yonghui presented on “Pesticide registration management and company’s precautions”. Mr. Zhao interpreted assessment factors in pesticide registration, and concerns of pesticide registration, and introduced document authorization, pharmacodynamic test and risk assessment when registering pesticides. Apart from that, Mr. Zhao has also summarized practical advice for 13 pesticides to help companies avoid detours in registration, which covers some popular products in market as followed:
1. Glyphosate: mixture mechanism of glyphosate and glufosinate has not been clarified, and mixture percentage differs greatly. Analyst is still working on some verification experiments to prove the reasonability of mixture. At the same time, glufosinate as compounding products, the mixture of glyphosate and glufosinate should also meet regulatory requirements of glufosinate.
2. Chlorfenapyr: chlorfenapyr is now approved to apply on cabbage to prohibit beet armyworm and plutella xylostella. But, due to chlorfenapyr‘s environmental risk on aquatic organism and bee, the committee suggest to not approve chlorfenapyr on rice field test and product registration. Environment risk review should be conducted on this commodity.
3. Indoxacarb: the National Pesticide Standardization Committee updated indoxacarb content on S isomer. Previous indoxacarb registration on technical material normally contains up to 70% active substance. The committee suggests registering on technical concentrate rather than active constituent.
4. Paraquat: since production and application of paraquat cause huge damage to human health, no more new registration will be approved in the future. Paraquat is clarified as highly toxic pesticide based on result of acute oral, dermal and inhalation toxicity tests. Since safety question has not been solved effectively, committee would no more accept or approve new or renewal registration. Current paraquat registration would be cancelled in a proper time.
5. Azoxystrobin: according to environmental risk assessment result, the application dosage and frequency should be decreased and the total dosage would be less than 525g per hectare (active substance).
6. Flubendiamide: based on flubendiamide’s environmental behavior, environmental toxicology testing and data, surface water monitoring data and risk assessment report, flubendiamide will cause unacceptable risk on vertebrate and huge risk on aquatic ecological environment when applying on rice. The committee would no more accept new or renewal flubendiamide’s registration on rice and cancel current registration on rice.
7. Ethofenprox: ethofenprox shows high toxicity on aquatic organism, and no more registration on rice would be approved. It means that rice market in China would close the door for ethofenprox temporarily.
8. Fipronil: routine pesticide residual monitoring results of agricultural products shows high fipronil residues, and this may lead to food safety and environment risk. Consequently, the registration process will be more strict and no more field test would be accepted or approve for those pesticides with fipronil. For fipronil suspension concentrates for seed dressing, since this product contains high quantity of active substance, the committee decides to refuse its registration.
9. Brassinolide: the Natioanl Pesticide Standardization Technical Committee is now building new national standard, the name of brassinolide include 24-BR,22,23,24-BR, 28-BR, 14-BR。Mr. Zhao emphasized that since there are 6 structures of brassinolide, original identification’s structure of technical material would differ from formulation’s structure, so the registration of this kind of product would stop. Among all 6 types of brassinolide, only 14-BR is extracted from pollen of canola and the rest are chemical synthesis, the committee has not decided whether 14-BR can be clarified as bio-chemical pesticide. Bio-chemical pesticides may exempt from some documents.
10. Ternary fungicides: in principle, ternary fungicides will not be approved in field test or new registration.
11. Seed treatment: Currently, approved ternary products only include herbicide and seed coating agent. Except seed treatments, the registration of pesticides mixed with fungicide would not be approved. Low toxic seed treatment is now exempted from some residual tests, but thiram is clarified as medium toxic product and cannot exempt from residual tests.
12. Thifluzamide: for mixed pesticide preparation with thifluzamide, due to application frequency of efficacy review is higher than the highest application frequency of residual reviews, more data should be provide to prove the product’s efficiency and safety. This is also the main reason that thifluzamide cannot achieve registration certification.
13. Dinotefuran: residual reports of dinotefuran water Dispersible Granules does not include two metabolite data that referring to dietary risk, so the registration of dinotefuran products would be stopped.
It shows that risk assessment has effective influence on pesticide registration. Lots of registration amendment is established on risk assessment result. Also, with the implement of the strictest ever food safety law, pesticide residual issues will also affect pesticide compliance. Pay close attention related policies would contribute to make right decision when developing products.
